This has to be browsed, in detail, to be appreciated: a version of Dutch artist M.C. Escher's print "Relativity" made . . . of Legos ?
Yes, indeedy! In my college days I had a poster of Escher's print that I kept for years by the stairway in whatever townhouse I was squatting in. And here's the link to the Sci American article with a 'slide show' with similar works of 'artistic illusion' that led me to this.